Investigation of relationships between serum lactate, acute phase proteins, pro/ antiinflammatory cytokine levels, and metritis formation in Holstein dairy heifers
نویسندگان
چکیده
The main purpose of this investigation was to identify and suggest suitable early screening inflammatory markers for the diagnosis uterine infections such as acute septic metritis (ASM) in Holstein heifers. In addition, achieve above -mentioned aim, objectives present study were tried determine relationship between blood serum lactate, phase proteins (APPs), pro/anti cytokine levels, formation For purpose, 250 heifers which 11-13 months old, chosen material. After conceived, samples collected at 8th 4th weeks before parturition. postpartum period, animals with ASM (n = 15) healthy identified, taken. Lactate, amyloid-A (SAA), haptoglobin (Hp), Interleukin-1beta (IL-1 ß), IL-6, IL-8, IL-10, tumor necrosis factor-alpha (TNF - α) levels measured from these samples. Acute-phase proteins, pro anti statistically compared. Heifers had a significantly greater concentration IL-6 SAA versus prepartum week. it determined that IL-1ß, TNF-α, higher week parturition group than those group. When all findings are evaluated together, suggested can be used biomarkers preliminary important processes ASM.
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ژورنال
عنوان ژورنال: Turkish Journal of Veterinary & Animal Sciences
سال: 2023
ISSN: ['1300-0128', '1303-6181']
DOI: https://doi.org/10.55730/1300-0128.4284